Cyclic HPMPC
Cat. No.：YN252205
| 产品名称: | Cyclic HPMPC |
| CAS No.: | 60084-10-8 |
| Chemical Name: | 2-β-D-Ribofuranosyl-4-thiazolecarboxamide; CI 909; NSC 286-193; NSC 286193; Riboxamide; TCAR; Tiazofurine; 2-β-D-Ribofuranosylthiazole-4-carboxamide; |
| Synonyms: | 噻唑呋林; NSC 286193; Riboxamide |
| 分子量: | 260.27 |
| 分子式: | C9H12N2O5S |
| SMILES: | O=C(C1=CSC([C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O)=N1)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Tiazofurin (NSC 286193) 是一种合成的核苷类似物，具有抗肿瘤活性。Tiazofurin 在细胞内合成为tiazole-4-carboxamide adenine dinucleotide (TAD)，TAD 是 IMP 脱氢酶 (IMPDH) 的有效抑制剂。Tiazofurin 还具有抗正痘病毒 (orthopoxvirus) 和抗天花病毒活性。 |
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Streeter, D.G. et al.: Biochem. Biophys. Res. Comm., 115, 544 (1983)
Boritzki, T. et al.: Biochem. Pharmacol., 34, 1109 (1985)
Malek, K. et al.: Leuk. Res., 28, 1125 (2004)
