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Pirlindole

Cat. No.:YN252207

  • CAS No. :60762-57-4

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    • 生物活性
    • 参考文献
    • 产品名称: Pirlindole
      CAS No.: 60762-57-4
      Chemical Name: 2,3,3a,4,5,6-hexahydro-8-methyl-1H-pyrazino[3,2,1-jk]carbazole
      Synonyms:Pirlindole. Lifril, Pyrazidol,
      分子量:226.3
      分子式:C15H18N2
      SMILES:CC1=CC=C(N2C3=C4CCCC3NCC2)C4=C1
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Pirlindole 是一种可逆的选择性MAO-A抑制剂。Pirlindole 也是肠病毒 D68 和柯萨奇病毒 B3 (CV-B3) 的抑制剂。
      IC50和靶点:
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    • Bruhwyler, J., Liégeois, J.F., and Géczy, J.Pirlindole: A selective reversible inhibitor of monoamine oxidase A. A review of its preclinical propertiesPharmacol. Res.36(1),23-33(1997)

      Morais, M., Santos, P.A., Mateus-Pinheiro, A., et al.The effects of chronic stress on hippocampal adult neurogenesis and dendritic plasticity are reversed by selective MAO-A inhibitionJ. Psychopharmacol.28(12),1178-1183(2014)

      Ulferts, R., de Boer, S.M., van der Linden, L., et al.Screening of a library of FDA-approved drugs identifies several enterovirus replication inhibitors that target viral protein 2CAntimicrob. Agents Chemother.60(5),2627-2638(2016)

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