KIN101
Cat. No.:YN252209
CAS No. :610753-87-2
产品名称: | KIN101 |
CAS No.: | 610753-87-2 |
Chemical Name: | 3-(4-bromophenyl)-7-[(methylsulfonyl)oxy]-4H-1-benzopyran-4-one |
Synonyms: | |
分子量: | 395.22554 |
分子式: | C16H11BrO5S |
SMILES: | O=C1C(C2=CC=C(Br)C=C2)=COC3=CC(OS(=O)(C)=O)=CC=C13 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | KIN101 是有效的 RNA 病毒 (RNA viral) 抑制剂,对流感病毒 (influenza virus) 和登革热病毒 (DNV) 的IC50分别为 2 μM,>5 μM。KIN101 是一种IRF-3依赖性信号传导的异黄酮激动剂,可以诱导 IRF-3 核易位。KIN101 具有针对 RNA 病毒的广谱活性。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Bedard, K.M., Wang, M.L., Proll, S.C., et al.Isoflavone agonists of IRF-3 dependent signaling have antiviral activity against RNA virusesJ. Virol.86(13),7334-7344(2012)