K6PC-5
Cat. No.：YN252229
CAS No. ：756875-51-1
| 产品名称: | K6PC-5 |
| CAS No.: | 756875-51-1 |
| Chemical Name: | 2-hexyl-N-[2-hydroxy-1-(hydroxymethyl)ethyl]-3-oxo-decanamide |
| Synonyms: | K6PC-5; K6PC 5; K6PC5 |
| 分子量: | 343.50142 |
| 分子式: | C19H37NO4 |
| SMILES: | O=C(C(CCCCCC)C(CCCCCCC)=O)NC(CO)CO |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | K6PC-5，一种神经酰胺衍生物，是一种鞘氨醇激酶 1 (SPHK1) 激活剂，可引起细胞内钙水平的短暂快速升高。K6PC-5 用于研究涉及异常角质形成细胞的皮肤疾病、神经退行性疾病和病毒感染。 |
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Hong, J.H., Youm, J.K., Kwon, M.J., et al.K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signalingJ. Invest. Dermatol.128,2166-2178(2008)
Liu, H., Zhang, Z., Xu, M., et al.K6PC-5 activates SphK1-Nrf2 signaling to protect neuronal cells from oxygen glucose deprivation/re-oxygenationCell Physiol. Biochem.51(4),1908-1920(2018)
Park, H.-y., Youm, J.-K., Kwon, M.J., et al.K6PC-5, a novel sphingosine kinase activator, improves long-term ultraviolet light-exposed aged murine skinExp. Dermatol.17(1),829-836(2008)
