Fuscin
Cat. No.：YN252240
| 产品名称: | Fuscin |
| CAS No.: | 83-85-2 |
| Chemical Name: | 9,10-dihydro-5-hydroxy-4,8,8-trimethyl-2H,4H-benzo[1,2-b:4,3-c']dipyran-2,6(8H)-dione |
| Synonyms: | |
| 分子量: | 276.28454 |
| 分子式: | C15H16O5 |
| SMILES: | O=C1OC(C)C(C2=C1)=C(O)C(C3=C2CCC(C)(C)O3)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Fuscin，一种真菌代谢物，CCR5受体拮抗剂，具有抗HIV作用的。Fuscin 是一种呼吸和氧化磷酸化抑制剂，也是一种线粒体 SH 依赖性转运连接功能的抑制剂。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Vignais, P.V., and Vignais, P.M.Effect of SH reagents on atractyloside binding to mitochondria and ADP translocation. Potentiation by ADP and its prevention by uncoupler FCCPFEBS Lett.26(1),27-31(1972)
Vignais, P.M., and Vignais, P.V.Fuscin, an inhibitor of mitochondrial SH-dependent transport-linked functionsBiochim. Biophys. Acta325(3),357-374(1973)
Yoganathan, K., Rossant, C., Ng, S., et al.10-Methoxydihydrofuscin, fuscinarin, and fuscin, novel antagonists of the human CCR5 receptor from Oidiodendron griseumJ. Nat. Prod.66(8),1116-1117(2003)
