Cefprozil
Cat. No.:YN252265
产品名称: | Cefprozil |
CAS No.: | 92665-29-7 |
Chemical Name: | (6R,7R)-7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-(1-propen-1-yl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
Synonyms: | 头孢丙烯 |
分子量: | 389.4 |
分子式: | C18H19N3O5S |
SMILES: | O=C(O)C1=C(/C=C/C)CS[C@@]([C@@H]2NC([C@H](N)C3=CC=C(O)C=C3)=O)([H])N1C2=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Cefprozil monohydrate (Cefzil) 是第二代头孢菌素类抗生素。 |
IC50和靶点: | |
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Tomatsu, K., Ando, S., Masuyoshi, S., et al.In vitro and in vivo evaluations of BMY-28100, a new oral cephalosporinJ. Antibiot. (Tokyo)40(8),1175-1183(1987)
Peric, M., Browne, F.A., Jacobs, M.R., et al.Activity of nine oral agents against gram-positive and gram-negative bacteria encountered in community-acquired infections: Use of pharmacokinetic/pharmacodynamic breakpoints in the comparative assessment of beta-lactam and macrolide antimicrobial agentsClin. Ther.25(1),169-177(2003)
Nagai, K., Davies, T.A., Jacobs, M.R., et al.Effects of amino acid alterations in penicillin-binding proteins (PBPs) 1a, 2b, and 2x on PBP affinities of penicillin, ampicillin, amoxicillin, cefditoren, cefuroxime, cefprozil, and cefaclor in 18 clinical isolates of penicillin-susceptible, -intermediate, and -resistant pneumococciAntimicrob. Agents Chemother.46(5),1273-1280(2002)