Cabotegravir sodium
Cat. No.：YN252276
CAS No. ：1051375-13-3
| 产品名称: | Cabotegravir sodium |
| CAS No.: | 1051375-13-3 |
| Chemical Name: | |
| Synonyms: | 卡博特韦钠; GSK-1265744 sodium; S/GSK1265744 sodium |
| 分子量: | 427.33404 |
| 分子式: | C19H16N3O5F2-.Na+ |
| SMILES: | [Na+].FC1C=C(F)C(=CC=1)CNC(=O)C2C(=O)C([O-])=C3N(C=2)C[C@@H]4N([C@@H](C)CO4)C3=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Cabotegravir (GSK-1265744) sodium 一种具有口服活性且长效的HIV 整合酶 (HIV integrase) 链转移抑制剂，也是有机阴离子转运蛋白 1/3 (OAT1/OAT3) 抑制剂，对HIVADA、OAT3 和 OAT1 的IC50分别为 2.5 nM、0.41 μM 和 0.81 μM。Cabotegravir sodium 主要由尿苷二磷酸葡萄糖醛酸转移酶 (UGT) 1A1 代谢，与其他抗逆转录病毒活性分子 (ARVs) 相互作用的可能性较低。Cabotegrav |
| IC50和靶点: | |
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| Solvent & Solubility: |
