LDC4297 hydrochloride
Cat. No.:YN252336
CAS No. :2319747-14-1
产品名称: | LDC4297 hydrochloride |
CAS No.: | 2319747-14-1 |
Chemical Name: | |
Synonyms: | |
分子量: | 468.98 |
分子式: | C23H29ClN8O |
SMILES: | CC(C)C1=C(N2N=C1)N=C(OC3CNCCC3)N=C2NCC4=CC=CC=C4N5C=CC=N5.[H]Cl |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | LDC4297 hydrochloride 是CDK7的选择性抑制剂,IC50值为 0.13 nM。LDC4297 hydrochloride 抑制人巨细胞病毒 (HCMV) 复制,EC50值为 24.5 nM。LDC4297 hydrochloride 具有广谱的抗病毒活性,对疱疹病毒,腺病毒,痘病毒,逆转录病毒和正粘病毒的EC50值为 0.02-1.21 μM。LDC4297 hydrochloride 可用于感染的研究。 |
IC50和靶点: | [{name:"CDK7:0.13 nM (IC50)"},{name: "166v VP22-GFP:0.02 μM (EC50)"},{name: "01-6332:0.27 μM (EC50)"},{name: "HIV-1 (NL4.3 strain):1.04 μM (EC50)"},{name: "4LIG7:1.13 μM (EC50)"}] |
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Clinical Trial: | |
Solvent & Solubility: |