Astodrimer
Cat. No.:YN252397
产品名称: | Astodrimer |
CAS No.: | 55396-45-7 |
Chemical Name: | 2-nonyl-4(1H)-quinolinone |
Synonyms: | 2-Nonylquinolin-4(1H |
分子量: | 271.4 |
分子式: | C18H25NO |
SMILES: | O=C1C=C(CCCCCCCCC)NC2=C1C=CC=C2 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Pseudane IX 是一种可以从Ruta angustifolia叶子中分离得到的化合物,具有较强的抗HCV活性,其IC50值为1.4 μg/mL。 Pseudane IX 可以降低HCVRNA 复制和病毒蛋白合成水平。 |
IC50和靶点: | |
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Wahyuni, T.S., Widyawaruyanti, A., Lusida, M.I., et al.Inhibition of hepatitis C virus replication by chalepin and pseudane IX isolated from Ruta angustifolia leavesFitoterapia99,276-283(2014)
Biavatti, M.W., Vieira, P.C., da Silva, F.d.G.F., et al.Biological activity of quinoline alkaloids from Raulinoa echinata and x-ray structure of flindersiamineJ. Braz. Chem. Soc.13(1),66-70(2002)
Jin, H.Z., Lee, J.H., Lee, D., et al.Quinolone alkaloids with inhibitory activity against nuclear factor of activated T cells from the fruits of Evodia rutaecarpaBiol. Pharm. Bull.27(6),926-928(2004)
Ortori, C.A., Dubern, J.-F., Chhabra, S.R., et al.Simultaneous quantitative profiling of N-acyl-L-homoserine lactone and 2-alkyl-4(1H)-quinolone families of quorum-sensing signaling molecules using LC-MS/MSAnal. Bioanal. Chem.399(2),839-850(2011)