Pritelivir mesylate hydrate
Cat. No.:YN252408
CAS No. :908112-37-8
产品名称: | Pritelivir mesylate hydrate |
CAS No.: | 908112-37-8 |
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分子量: | 410.518 |
分子式: | C23H30N4O3 |
SMILES: | 暂无 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | AT-533 是一种有效的Hsp90和HSV抑制剂。AT-533 通过阻断HIF-1α/VEGF/VEGFR-2信号通路抑制肿瘤生长和血管生成。AT-533 还抑制下游通路的激活,包括Akt/mTOR/p70S6K,Erk1/2和FAK。AT-533 抑制人脐静脉内皮细胞 (HUVEC) 的管形成、细胞迁移和侵袭。 |
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