Mafosfamide sodium salt
Cat. No.：YN270013
CAS No. ：84211-05-2
| 产品名称: | Mafosfamide sodium salt |
| CAS No.: | 84211-05-2 |
| Chemical Name: | rel-2-[[(2R,4R)-2-[Bis(2-chloroethyl)amino]tetrahydro-2-oxido-2H-1,3,2-oxazaphosphorin-4-yl]thio]ethanesulfonic Acid Sodium; Mafosfamid Sodium; Z 7557; cis-Mafosfamide Sodium; |
| Synonyms: | Z 7557 sodium salt; cis |
| 分子量: | 423.25 |
| 分子式: | C₉H₁₈Cl₂N₂NaO₅PS₂ |
| SMILES: | ClCCN([P@@]1(OCC[C@@H](SCCS(=O)(O[Na])=O)N1)=O)CCCl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mafosfamide sodium salt (Z 7557 sodium salt) 靶向核 DNA，形成 DNA 交联 (DNA cross-links) 并抑制 DNA 合成 (DNA synthesis)。Mafosfamide sodium salt 是一种环磷酰胺类似物，可以诱导成淋巴细胞样细胞凋亡 (apoptosis)。Mafosfamide sodium salt 具有抗肿瘤活性。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Roy, P., et al.: Drug Metab. Dispos., 27, 655
