Ecteinascidin 770
Cat. No.:YN270028
产品名称: | Ecteinascidin 770 |
CAS No.: | 114899-80-8 |
Chemical Name: | Spiro[6,16-(epithiopropanoxymethano)-7,13-imino-12H-1,3-dioxolo[7,8]isoquino[3,2-b][3]benzazocine-20,1'(2'H)-isoquinoline]-14-carbonitrile, 5-(acetyloxy)-3',4',6,6a,7,13,14,16-octahydro-6',8-dihydroxy-7',9-dimethox |
Synonyms: | Ecteinascidine 770; Et-770 |
分子量: | 770.85 |
分子式: | C₄₀H₄₂N₄O₁₀S |
SMILES: | N#C[C@@H]([C@@]1([H])N(C)[C@]2([H])C3=C(C=C(C)C(OC)=C3O)C1)N4[C@@]2([H])[C@@](SC[C@@]5(NCC6)C7=C6C=C(O)C(OC)=C7)([H])C8=C(C(OCO9)=C9C(C)=C8OC(C)=O)[C@]4([H])COC5=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Ecteinascidin 770 (ET-770)是具有抗癌活性的1,2,3,4-四氢异喹啉生物碱,抑制U373MG cells的IC50值为4.83 nM。 |
IC50和靶点: | |
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Swain, Shasank S., et al.: Eur. J. Med. Chem., 232, 114173 (2022)