RAD51 Inhibitor B02
Cat. No.：YN270031
CAS No. ：1290541-46-6
| 产品名称: | RAD51 Inhibitor B02 |
| CAS No.: | 1290541-46-6 |
| Chemical Name: | 3-(phenylmethyl)-2-[(1E)-2-(3-pyridinyl)ethenyl]-4(3H)-quinazolinone |
| Synonyms: | B02 |
| 分子量: | 339.39 |
| 分子式: | C₂₂H₁₇N₃O |
| SMILES: | O=C1N(CC2=CC=CC=C2)C(/C=C/C3=CC=CN=C3)=NC4=C1C=CC=C4 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RAD51 Inhibitor B02 (B02)是人RAD51的抑制剂，IC50值为27.4 μM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Huang, F., Motlekar, N.A., Burgwin, C.M., et al.Identification of specific inhibitors of human RAD51 recombinase using high-throughput screeningACS Chem. Biol.6(6),628-635(2011)
Huang, F., Mazina, O.M., Zentner, I.J., et al.Inhibition of homologous recombination in human cells by targeting RAD51 recombinaseJ. Med. Chem.55(7),3011-3020(2012)
Huang, F., and Mazin, A.V.A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenograftsPLoS One9(6),e100993(2014)
