Dinaciclib
Cat. No.：YN270062
CAS No. ：779353-01-4
| 产品名称: | Dinaciclib |
| CAS No.: | 779353-01-4 |
| Chemical Name: | 1-[3-ethyl-7-[[(1-oxido-3-pyridinyl)methyl]amino]pyrazolo[1,5-a]pyrimidin-5-yl]-2S-piperidineethanol |
| Synonyms: | SCH 727965 |
| 分子量: | 396.49 |
| 分子式: | C₂₁H₂₈N₆O₂ |
| SMILES: | OCC[C@H]1N(CCCC1)C2=NC3=C(C=NN3C(NCC4=C[N+]([O-])=CC=C4)=C2)CC |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Dinaciclib (SCH 727965) 是一种有效的选择性CDK抑制剂，抑制CDK2，CDK5，CDK1和CDK9的IC50分别为 1 nM，1 nM，3 nM 和 4 nM。 |
| IC50和靶点: | [{name:"CDK2:1 nM (IC50)"},{name: "CDK5:1 nM (IC50)"},{name: "CDK1:3 nM (IC50)"},{name: "CDK9:4 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Parry, D., Guzi, T., Shanahan, F., et al.Dinaciclib (SCH 727965), a novel and potent cyclin-dependent kinase inhibitorMol. Cancer Ther.9(8),2344-2353(2010)
