SCR7 pyrazine
Cat. No.：YN270072
CAS No. ：14892-97-8
| 产品名称: | SCR7 pyrazine |
| CAS No.: | 14892-97-8 |
| Chemical Name: | 6,7-Diphenyl-2-thio-lumazine; |
| Synonyms: | SCR7 吡嗪,SCR7 |
| 分子量: | 332.38 |
| 分子式: | C₁₈H₁₂N₄OS |
| SMILES: | O=C1NC(NC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N=C12)=S |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | SCR7 pyrazine 是一种 DNA 连接酶 IV (DNA ligase IV) 抑制剂，它以连接酶 IV 依赖的方式阻断非同源末端连接 (NHEJ)。SCR7 pyrazine 也是一种CRISPR/Cas9的增强子，可提高 Cas9 介导的同源性定向修复 (HDR) 的效率。SCR7 pyrazine 诱导细胞凋亡 (apoptosis) 并具有抗癌活性。 |
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Ochoa, C. et al.: Med. Chem. Res., 7, 530 (1997)
Bhatt, H. et al.: Chem. biol. Drugs Des., 83, 154 (2014)
