BTZO-1
Cat. No.：YN270093
| 产品名称: | BTZO-1 |
| CAS No.: | 99420-15-2 |
| Chemical Name: | 2-(2-pyridinyl)-4H-1,3-benzothiazin-4-one |
| Synonyms: | BTZO-1|BTZO 1 |
| 分子量: | 240.28 |
| 分子式: | C₁₃H₈N₂OS |
| SMILES: | O=C1N=C(C2=NC=CC=C2)SC3=CC=CC=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BTZO-1 可以结合巨噬细胞迁移抑制因子 (MIF)，结合的Kd值为 68.6 nM，并且其结合需要 N 末端 Pro1。BTZO-1 可以激活抗氧化反应元件 (ARE) 介导的基因表达，并在体外抑制氧化应激诱导的心肌细胞凋亡 (apoptosis)。 |
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Kimura, H., Sato, Y., Tajima, Y., et al.BTZO-1, a cardioprotective agent, reveals that macrophage migration inhibitory factor regulates ARE-mediated gene expressionChem. Biol.17(12),1282-1294(2010)
