alpha-Bisabolol
Cat. No.：YN270144
| 产品名称: | alpha-Bisabolol |
| CAS No.: | 515-69-5 |
| Chemical Name: | (αR,1R)-rel-α,4-dimethyl-α-(4-methyl-3-penten-1-yl)-3-cyclohexene-1-methanol |
| Synonyms: | alpha-红没药醇 |
| 分子量: | 222.37 |
| 分子式: | C₁₅H₂₆O |
| SMILES: | C/C(C)=C\CC[C@@](O)([C@@H]1CCC(C)=CC1)C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | alpha-Bisabolol 是一种存在天然精油中无毒的倍半萜烯醇，具有抗癌活性。alpha-Bisabolol 通过诱导细胞周期停滞、线粒体死亡，和抑制 PI3K/Akt 信号通路，对 A549 NSCLC 细胞产生抗癌作用 (IC50= 15 μM)。alpha-Bisabolol 能强有力地诱导胶质瘤细胞凋亡。 |
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Cavalieri, E., Mariotto, S., Fabrizi, C., et al.ɑ-Bisabolol, a nontoxic natural compound, strongly induces apoptosis in glioma cellsBiochem. Biophys. Res. Commun.315(3),589-594(2004)
Cavalieri, E., Rigo, A., Bonifacio, M., et al.Pro-apoptotic activity of ɑ-bisabolol in preclinical models of primary human acute leukemia cellsJ. Transl. Med.9,45(2011)
