RIPGBM
Cat. No.：YN270160
CAS No. ：355406-76-7
| 产品名称: | RIPGBM |
| CAS No.: | 355406-76-7 |
| Chemical Name: | N-[1,4-dihydro-1,4-dioxo-3-[(phenylmethyl)amino]-2-naphthalenyl]-N-[(4-fluorophenyl)methyl]-acetamide |
| Synonyms: | RIPGBM| |
| 分子量: | 428.45 |
| 分子式: | C₂₆H₂₁FN₂O₃ |
| SMILES: | CC(N(C(C1=O)=C(NCC2=CC=CC=C2)C(C3=C1C=CC=C3)=O)CC4=CC=C(F)C=C4)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | RIPGBM 是一种选择性的细胞凋亡 (apoptosis) 诱导剂，诱导多形性成胶质细胞瘤 (GBM) 癌症干细胞 (CSCs) 凋亡，EC50≤500 nM。 |
| IC50和靶点: | |
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| Solvent & Solubility: |
Lucki, N.C., Villa, G.R., Vergani, N., et al.A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancerProc. Natl. Acad. Sci. USA116(13),6435-6440(2019)
