(6R)-FR054
Cat. No.:YN270177
CAS No. :10378-06-0
产品名称: | (6R)-FR054 |
CAS No.: | 10378-06-0 |
Chemical Name: | (3aR,5R,6R,7R,7aR)-5-(Acetoxymethyl)-2-methyl-3a,6,7,7a-tetrahydro-5H-pyrano[3,2-d]oxazole-6,7-diyl Diacetate; |
Synonyms: | (3AR,7AR)-5-(乙酰氧基甲基)-2-甲基-5,6,7,7A-四氢-3AH-吡喃并[3,2-D]噁唑-6,7-叉基二醋酸盐,FR054 |
分子量: | 329.30 |
分子式: | C₁₄H₁₉NO₈ |
SMILES: | CC1=N[C@@]([C@@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H](COC(C)=O)O2)([H])[C@@]2([H])O1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | (6R)-FR054 是FR054 的一个活性异构体。FR054 是HBP酶PGM3的抑制剂,具有显著的抗乳腺癌活性。FR054 可诱导内质网应激和 ROS 依赖的细胞凋亡。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Koizumi, M., et al.: PCT Int. Appl. 278pp. (2019)