Batabulin sodium
Cat. No.：YN270237
| 产品名称: | Batabulin sodium |
| CAS No.: | 195533-98-3 |
| Chemical Name: | 2,3,4,5,6-pentafluoro-N-(3-fluoro-4-methoxyphenyl)-benzenesulfonamide, monosodium salt |
| Synonyms: | T138067 sodium |
| 分子量: | 393.24 |
| 分子式: | C₁₃H₆F₆NNaO₃S |
| SMILES: | O=S(C1=C(F)C(F)=C(F)C(F)=C1F)([N-]C2=CC=C(OC)C(F)=C2)=O.[Na+] |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Batabulin sodium (T138067 sodium) 是一种抗肿瘤剂，可与 β-微管蛋白同种型的子集共价且选择性地结合，从而破坏微管 (microtubule) 聚合。Batabulin sodium 影响细胞形态并导致细胞周期停滞，最终诱导凋亡性细胞死亡。 |
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Shan, B., Medina, J.C., Santha, E., et al.Selective, covalent modification of β-tubulin residue Cys-239 by T138067, an antitumor agent with in vivo efficacy against multidrug-resistant tumorsProc. Natl. Acad. Sci. USA96(10),5686-5691(1999)
