Lomustine
Cat. No.：YN270256
| 产品名称: | Lomustine |
| CAS No.: | 13010-47-4 |
| Chemical Name: | N-(2-chloroethyl)-N'-cyclohexyl-N-nitroso-urea |
| Synonyms: | 洛莫司汀; CCNU; NSC 79037 |
| 分子量: | 233.70 |
| 分子式: | C₉H₁₆ClN₃O₂ |
| SMILES: | O=C(NC1CCCCC1)N(CCCl)N=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Lomustine (CCNU; NSC 79037) 是一种 DNA 烷化剂 (DNA alkylator)，具有抗肿瘤活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Kohn, K.W.Interstrand cross-linking of DNA by 1,3-bis(2-chloroethyl)-1-nitrosourea and other 1-(2-haloethyl)-1-nitrosoureasCancer Res.37(5),1450-1454(1977)
Siddik, Z.H.Mechanisms of action of cancer chemotherapeutic agents: DNA-interactive alkylating agents and antitumour platinum-based drugsThe Cancer Handbook 1st Edition,(2005)
Osieka, R., Glatte, P., Pannenbäcker, R., et al.Therapeutic evaluation of five nitrosoureas in a human melanoma xenograft systemCancer Chemother. Pharmacol.11(3),147-152(1983)
