Mitotane
Cat. No.：YN270259
| 产品名称: | Mitotane |
| CAS No.: | 53-19-0 |
| Chemical Name: | 1-chloro-2-[2,2-dichloro-1-(4-chlorophenyl)ethyl]-benzene |
| Synonyms: | 米托坦; 2,4′-DDD; o,p'-DDD |
| 分子量: | 320.04 |
| 分子式: | C₁₄H₁₀Cl₄ |
| SMILES: | ClC1=CC=C(C(C2=CC=CC=C2Cl)C(Cl)Cl)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Mitotane(2,4′-DDD)是DDD的同分异构体和DDT的衍生物，有抗癌活性，可作用于肾上腺皮质癌。 |
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Hescot, S., Slama, A., Lombès, A., et al.Mitotane alters mitochondrial respiratory chain activity by inducing cytochrome c oxidase defect in human adrenocortical cellsEndocr. Relat. Cancer20(3),371-381(2013)
Hart, M.M., Reagan, R.L., and Adamson, R.H.The effect of isomers of DDD on the ACTH-induced steroid output, histology and ultrastructure of the dog adrenal cortexToxicol. Appl. Pharmacol.24(1),101-113(1973)
