Adarotene
Cat. No.：YN270292
CAS No. ：496868-77-0
| 产品名称: | Adarotene |
| CAS No.: | 496868-77-0 |
| Chemical Name: | (2E)-3-(4′-hydroxy-3′-tricyclo[3.3.1.13,7]dec-1-yl[1,1′-biphenyl]-4-yl)-2-propenoic acid |
| Synonyms: | ST1926 |
| 分子量: | 374.47 |
| 分子式: | C₂₅H₂₆O₃ |
| SMILES: | O=C(O)/C=C/C1=CC=C(C2=CC=C(O)C(C3(C4)CC5CC4CC(C5)C3)=C2)C=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Adarotene 是一种有效的apoptosis诱导剂，通过产生 DNA 损伤，来阻止人类肿瘤细胞的增殖。 |
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Cincinelli, R., Dallavalle, S., Merlini, L., et al.A novel atypical retinoid endowed with proapoptotic and antitumor activityJ. Med. Chem.46(6),909-912(2003)
Nasr, R.R., Hmadi, R.A., El-Eit, R.M., et al.ST1926, an orally active synthetic retinoid, induces apoptosis in chronic myeloid leukemia cells and prolongs survival in a murine modelInt. J. Cancer137(3),698-709(2015)
