Menin-MLL inhibitor MI-2
Cat. No.:YN270299
CAS No. :1271738-62-5
产品名称: | Menin-MLL inhibitor MI-2 |
CAS No.: | 1271738-62-5 |
Chemical Name: | 4-[4-(4,5-dihydro-5,5-dimethyl-2-thiazolyl)-1-piperazinyl]-6-propyl-thieno[2,3-d]pyrimidine |
Synonyms: | MI-2,Menin-MLL inhibitor 2,Menin-MLL Inhibitor,MI 2,MI2 |
分子量: | 375.55 |
分子式: | C₁₈H₂₅N₅S₂ |
SMILES: | CCCC1=CC2=C(N3CCN(C4=NCC(C)(C)S4)CC3)N=CN=C2S1 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Menin-MLL inhibitor MI-2 抑制Menin-MLL相互作用,IC50为 446±28 nM。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Grembecka, J., He, S., Shi, A., et al.Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemiaNat. Chem. Biol.8(3),277-284(2012)