CPI-360
Cat. No.：YN270329
CAS No. ：1802175-06-9
| 产品名称: | CPI-360 |
| CAS No.: | 1802175-06-9 |
| Chemical Name: | N-[(1,2-dihydro-4-methoxy-6-methyl-2-oxo-3-pyridinyl)methyl]-2-methyl-1-[(1R)-1-(tetrahydro-2H-pyran-4-yl)ethyl]-1H-indole-3-carboxamide |
| Synonyms: | CPI360,CPI 360 |
| 分子量: | 437.53 |
| 分子式: | C₂₅H₃₁N₃O₄ |
| SMILES: | CC(N1)=CC(OC)=C(CNC(C2=C(C)N([C@H](C)C3CCOCC3)C4=CC=CC=C24)=O)C1=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | CPI-360是一种有效的选择性EZH2抑制剂, 作用于wt EZH2 和 Y641N EZH2时, IC50分别为0.5 nM和2.5 nM。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Bradley, W.D., Arora, S., Busby, J., et al.EZH2 inhibitor efficacy in non-Hodgkin's lymphoma does not require suppression of H3K27 monomethylationChem. Biol.21,1-13(2014)
