Omigapil maleate
Cat. No.：YN270340
CAS No. ：200189-97-5
| 产品名称: | Omigapil maleate |
| CAS No.: | 200189-97-5 |
| Chemical Name: | N-methyl-N-2-propyn-1-yl-dibenz[b,f]oxepin-10-methanamine, (2Z)-2-butenedioate |
| Synonyms: | CGP3466B maleate |
| 分子量: | 391.42 |
| 分子式: | C₂₃H₂₁NO₅ |
| SMILES: | C#CCN(C)CC1=CC2=CC=CC=C2OC3=CC=CC=C13.O=C(O)/C=C\C(O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Omigapil maleate 是一种具有口服活性的GAPDH亚硝基化抑制剂，可消除 Aβ1-42诱导的小鼠 tau 乙酰化，记忆障碍和运动功能障碍，Omigapil maleate 具有研究阿尔茨海默症的潜力。Omigapil maleate (CGP3446B maleate) 是一种有效的凋亡 (apoptosis) 抑制剂。Omigapil maleate 可用于研究先天性肌营养不良 (CMD)。 |
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Olanow, C.W., Schapira, A.H., LeWitt, P.A., et al.TCH346 as a neuroprotective drug in Parkinson's disease: a double blind, randomised, controlled trialLancet. Neurol.5(12),1013-1020(2006)
