Riviciclib hydrochloride
Cat. No.：YN270343
CAS No. ：920113-03-7
| 产品名称: | Riviciclib hydrochloride |
| CAS No.: | 920113-03-7 |
| Chemical Name: | |
| Synonyms: | P276-00 |
| 分子量: | 438.30 |
| 分子式: | C₂₁H₂₁Cl₂NO₅ |
| SMILES: | [H]Cl.O=C1C=C(C2=CC=CC=C2Cl)OC3=C([C@@H]4CCN(C)[C@H]4CO)C(O)=CC(O)=C31 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Riviciclib hydrochloride (P276-00) 是有效的CDK抑制剂，抑制CDK9-cyclinT1，CDK4-cyclin D1，CDK1-cyclinB的IC50值分别为 20 nM，63 nM，79 nM。Riviciclib hydrochloride (P276-00) 对 Cisplatin 耐药性细胞具有抗肿瘤活性。 |
| IC50和靶点: | [{name:"CDK9- Cyclin T1:0.020 μM (IC50)"},{name: "cdk4-cyclin D1:0.063 μM (IC50)"},{name: "CDK1-Cyclin B:0.079 μM (IC50)"},{name: "cdk2-cyclin A:0.224 μM (IC50)"},{name: "cdk2-cyclin E:2.500 μM (IC50)"},{name: "cdk6-cyclin D3:0.396 μM (IC50)"},{name: "CDK9-cyclin H:2.900 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
