MDK83190
Cat. No.:YN270371
CAS No. :79183-19-0
产品名称: | MDK83190 |
CAS No.: | 79183-19-0 |
Chemical Name: | 1-[(3,4-dichlorophenyl)methyl]-1H-indole-2,3-dione |
Synonyms: | Apoptosis Activator 2 |
分子量: | 306.14 |
分子式: | C₁₅H₉Cl₂NO₂ |
SMILES: | O=C1N(CC2=CC=C(Cl)C(Cl)=C2)C3=C(C=CC=C3)C1=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | MDK83190 是一种有效的细胞凋亡 (apoptosis) 激活剂,诱导 Apaf-1 寡聚化,以 cyto-c 依赖性方式增加 procaspase-9 加工和 caspase-3 活化。 |
IC50和靶点: | |
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Solvent & Solubility: |
Nguyen, J.T., and Wells, J.A.Direct activation of the apoptosis machinery as a mechanism to target cancer cellsProc. Natl. Acad. Sci. USA100(13),7533-7538(2003)