BG45
Cat. No.：YN270376
CAS No. ：926259-99-6
| 产品名称: | BG45 |
| CAS No.: | 926259-99-6 |
| Chemical Name: | N-(2-aminophenyl)-2-pyrazinecarboxamide |
| Synonyms: | BG45;N-(2-Aminophenyl)pyrazine-2-carboxamide;12P6IK4ZUX;N-(2-Aminophenyl)-2-pyrazinecarboxamide;AOB4907;SYN5062;LMWPVSNHKACEKW-UHFFFAOYSA-N;BCP15990;s7689;AK501416;2-Pyrazinecarboxamide, N-(2-aminophenyl)-;B5949;Q27216142;Z2242032441 |
| 分子量: | 214.22 |
| 分子式: | C₁₁H₁₀N₄O |
| SMILES: | O=C(C1=NC=CN=C1)NC2=CC=CC=C2N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | BG45是一个HDAC I型抑制剂, 选择性抑制HDAC3 (IC50=289 nM). BG45抑制HDAC1/2/ 6, 效力大大降低 (IC50分别为2, 2.2, 和 >20μM)。 |
| IC50和靶点: | [{name:"HDAC3:0.289 μM (IC50)"},{name: "HDAC1:2.0 μM (IC50)"},{name: "HDAC2:2.2 μM (IC50)"},{name: "HDAC6:>20 μM (IC50)"}] |
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| Solvent & Solubility: |
Minami, J., Suzuki, R., Mazitschek, R., et al.Histone deacetylase 3 (HDAC3) as a novel therapeutic target in multiple myelomaLeukemia28(3),680-689(2014)
