Didesmethylrocaglamide
Cat. No.：YN270382
CAS No. ：177262-30-5
| 产品名称: | Didesmethylrocaglamide |
| CAS No.: | 177262-30-5 |
| Chemical Name: | |
| Synonyms: | Didesmethylrocaglamide; DDR; rocaglamide-derivative. |
| 分子量: | 477.51 |
| 分子式: | C₂₇H₂₇NO₇ |
| SMILES: | O=C([C@H]([C@H]1C2=CC=CC=C2)[C@@H](O)[C@]3(O)[C@@]1(C4=CC=C(OC)C=C4)OC5=CC(OC)=CC(OC)=C35)N |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Didesmethylrocaglamide 是一种 Rocaglamide 的衍生物，也是一种有效的真核起始因子 4A (eIF4A) 抑制剂。Didesmethylrocaglamide 具有有效的生长抑制活性，IC50为 5 nM。Didesmethylrocaglamide 抑制多种促进生长的信号通路，并诱导肿瘤细胞凋亡 (apoptosis)。抗肿瘤活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
