AT7519
Cat. No.：YN270407
CAS No. ：844442-38-2
| 产品名称: | AT7519 |
| CAS No.: | 844442-38-2 |
| Chemical Name: | |
| Synonyms: | N-(4-Piperidinyl)-4-(2,6-dichlorobenzoylamino)-1H-pyrazole-3-carboxamide;AT7519;4-(2,6-Dichlorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide;4-[(2,6-dichlorobenzoyl)amino]-N-4-piperidinyl1H-pyrazole-3-carboxamide;4-[(2,6-dichlorobenzoyl)amino]-N |
| 分子量: | 382.24 |
| 分子式: | C₁₆H₁₇Cl₂N₅O₂ |
| SMILES: | O=C(NC1=CNN=C1C(NC2CCNCC2)=O)C3=C(Cl)C=CC=C3Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | AT7519 是一种有效的CDK抑制剂，对 CDK1，CDK2，CDK4-CDK6 以及 CDK9 的IC50值分别为 210，47，100，13，170 和 <10 nM。 |
| IC50和靶点: | [{name:"CDK9/Cyclin T:10 nM (IC50)"},{name: "CDK5/p35:13 nM (IC50)"},{name: "cdk2/cyclin A:47 nM (IC50)"},{name: "Cdk4/cyclin D1:100 nM (IC50)"},{name: "cdk6/cyclin D3:170 nM (IC50)"},{name: "Cdk1/cyclin B:210 nM (IC50)"},{name: "CDK7/Cyclin H/MAT1:2400 nM (IC50)"},{name: "GSK3β:89 nM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
