TCS7010
Cat. No.：YN270410
CAS No. ：1158838-45-9
| 产品名称: | TCS7010 |
| CAS No.: | 1158838-45-9 |
| Chemical Name: | N-(2-chlorophenyl)-4-[[2-[[4-[2-(4-ethyl-1-piperazinyl)-2-oxoethyl]phenyl]amino]-5-fluoro-4-pyrimidinyl]amino]-benzamide |
| Synonyms: | Aurora A Inhibitor I |
| 分子量: | 588.08 |
| 分子式: | C₃₁H₃₁ClFN₇O₂ |
| SMILES: | O=C(C1=CC=C(C=C1)NC2=C(F)C=NC(NC3=CC=C(C=C3)CC(N4CCN(CC4)CC)=O)=N2)NC5=CC=CC=C5Cl |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | TCS7010 是有效，高度选择的Aurora A抑制剂，IC50值为 3.4 nM。 |
| IC50和靶点: | [{name:"Aurora A:3.4 nM (IC50)"},{name: "Aurora B:3.4 μM (IC50)"}] |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Aliagas-Martin, I., Burdick, D., Corson, L., et al.A class of 2,4-bisanilinopyrimidine Aurora A inhibitors with unusually high selectivity against Aurora BJ. Med. Chem.52(10),3300-3307(2009)
