Docetaxel Trihydrate
Cat. No.:YN270414
产品名称: | Docetaxel Trihydrate |
CAS No.: | 148408-66-6 |
Chemical Name: | |
Synonyms: | RP-56976 Trihydrate |
分子量: | 861.93 |
分子式: | C₄₃H₅₉NO₁₇ |
SMILES: | O=C(OC(C)(C)C)N[C@H]([C@H](C(O[C@@H]1C(C)=C([C@@H](O)C([C@@]2(C)[C@]([C@@](CO3)(OC(C)=O)[C@@]3([H])C[C@@H]2O)([H])[C@@H]4OC(C5=CC=CC=C5)=O)=O)C(C)(C)[C@@]4(O)C1)=O)O)C6=CC=CC=C6.O.O.O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Docetaxel Trihydrate (RP-56976 Trihydrate) 是一种抗肿瘤试剂,抑制微管解聚 (microtubule depolymerization) 的IC50值为 0.2 μM。Docetaxel Trihydrate 是紫杉醇的半合成类似物,能减弱 bcl-2 和 bcl-xL 基因表达的影响。Docetaxel Trihydrate 阻滞G2/M细胞周期,导致细胞凋亡 (apoptosis)。 |
IC50和靶点: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |