Busulfan-D8
Cat. No.：YN270421
| 产品名称: | Busulfan-D8 |
| CAS No.: | 116653-28-2 |
| Chemical Name: | 1,4-butane-1,1,2,2,3,3,4,4-d8-diol, dimethanesulfonate |
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| 分子量: | 254.35 |
| 分子式: | C₆H₆D₈O₆S₂ |
| SMILES: | CS(=O)(OC([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])OS(C)(=O)=O)=O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Busulfan-D8 is a deuterium labeled Busulfan. Busulfan is an alkyl sulfonate that acts as an alkylating antineoplastic agent. Busulfan forms both intra- and interstrand crosslinks on DNA. In mammals, Busulfan causes profound and prolonged reduction in the |
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Appelbaum, F.R.Optimizing the conditioning regimen for acute myeloid leukemiaBest Pract. Res. Clin. Haematol.22(4),543-550(2009)
Iwamoto, T., Hiraku, Y., Oikawa, S., et al.DNA intrastrand cross-link at the 5'-GA-3' sequence formed by busulfan and its role in the cytotoxic effectCancer Sci.95(5),454-458(2004)
Ponti, M., Souhami, R.L., Fox, B.W., et al.DNA interstrand crosslinking and sequence selectivity of dimethanesulphonatesBr. J. Cancer63(5),743-747(1991)
Copelan, E.A., and Deeg, H.J.Conditioning for allogeneic marrow transplantation in patients with lymphohematopoietic malignancies without the use of total body irradiationBlood80(7),1648-1658(1992)
