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Sodium Butyrate

Cat. No.:YN270424

  • CAS No. :156-54-7

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    • 生物活性
    • 参考文献
    • 产品名称: Sodium Butyrate
      CAS No.: 156-54-7
      Chemical Name: butanoic acid, sodium salt
      Synonyms:丁酸钠; Butanoic acid sodium salt
      分子量:110.09
      分子式:C₄H₇NaO₂
      SMILES:CCCC(O[Na])=O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Sodium Butyrate (Butanoic acid sodium salt) 是一种短链脂肪酸,可以抑制组蛋白去乙酰化酶。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Wang, M., Wichienchot, S., He, X., et al.In vitro colonic fermentation of dietary fibers: Fermentation rate, short-chain fatty acid production and changes in microbiotaTrends Food Sci. Technol.88(1),1-9(2019)

      Smith, J.G., Yokoyama, W.H., and German, J.B.Butyric acid from the diet: Actions at the level of gene expressionCrit. Rev. Food Sci. Nutr.38(4),259-297(1998)

      Waldecker, M., Kautenburger, T., Daumann, H., et al.Inhibition of histone-deacetylase activity by short-chain fatty acids and some polyphenol metabolites formed in the colonJ. Nutr. Biochem.19(9),587-593(2008)

      Decrion-Barthod, A.-Z., Bosset, M., Plissonnier, M.-L., et al.Sodium butyrate with UCN-01 has marked antitumour activity against cervical cancer cellsAnticancer Res.30(10),4049-4061(2010)

      Joseph, J., Mudduluru, G., Antony, S., et al.Expression profiling of sodium butyrate (NaB)-treated cells: identification of regulation of genes related to cytokine signaling and cancer metastasis by NaBOncogene23(37),6304-6315(2004)

      Chabanas, A., Khoury, E., Goeltz, P., et al.Effects of butyric acid on cell cycle regulation and induction of histone Hl° in mouse cells and tissue culture inducibility of Hl° in the late S-G2 phase of the cell cycleJ. Mol. Biol.183(2),141-151(1985)

      Chen, G., Ran, X., Li, B., et al.Sodium butyrate inhibits inflammation and maintains epithelium barrier integrity in a TNBS-induced inflammatory bowel disease mice modelEBioMedicine30(1),317-325(2018)

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