Brazilin
Cat. No.：YN270440
| 产品名称: | Brazilin |
| CAS No.: | 474-07-7 |
| Chemical Name: | 7,11bR-dihydro-benz[b]indeno[1,2-d]pyran-3,6aS,9,10(6H)-tetrol |
| Synonyms: | 巴西苏木素 |
| 分子量: | 286.28 |
| 分子式: | C₁₆H₁₄O₅ |
| SMILES: | OC1=CC=C([C@]2([H])[C@](CC3=C2C=C(O)C(O)=C3)(O)CO4)C4=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Brazilin 是一种来自几种热带硬木的心材的红色染料前体。Brazilin 抑制细胞增殖，促进细胞凋亡并通过 AMPK/mTOR 途径诱导自噬。Brazilin 显示出软骨保护和抗炎活性。 |
| IC50和靶点: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: |
Lee, H., Kang, S.W., Byun, H.S., et al.Brazilin limits inflammatory responses through induction of prosurvival autophagy in rheumatoid fibroblast-like synoviocytesPloS One10(8),e313(2015)
Du, W.-J., Guo, J.-J., Gao, M.-T., et al.Brazilin inhibits amyloid b-protein fibrillogenesis, remodels amyloid fibrils and reduces amyloid cytotoxicitSci. Rep.5(7992),(2015)
Tewtrakul, S., Tungcharoen, P., Sudsai, T., et al.Antiinflamatory and wound healing effects of Caesalpinia sappan L.Phytother. Res.29(6),850-856(2015)
Nirmal, N.P., and Panichayupakaranant, P.Antioxidant, antibacterial, and anti-inflammatory activities of standardized brazilin-rich Caesalpinia sappan extractPharm. Biol.53(9),1339-1343(2015)
Kim, J., Lee, H.K., Chang, T.-S., et al.Inhibitory effect of brazilin on osteoclast differentiation and its mechanism of actionInt. Immunopharmacol.29(2),628-634(2015)
