Apocynin
Cat. No.:YN270442
产品名称: | Apocynin |
CAS No.: | 498-02-2 |
Chemical Name: | 1-(4-hydroxy-3-methoxyphenyl)-ethanone |
Synonyms: | 香草乙酮; Acetovanillone |
分子量: | 166.17 |
分子式: | C₉H₁₀O₃ |
SMILES: | CC(C1=CC=C(O)C(OC)=C1)=O |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Apocynin是选择性的NADPH-氧化酶抑制剂,IC50为10 μM。 |
IC50和靶点: | |
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Heumüller, S., Wind, S., Barbosa-Sicard, E., et al.Apocynin is not an inhibitor of vascular NADPH oxidases but an antioxidantHypertension51(2),211-217(2008)
Impellizzeri, D., Esposito, E., Mazzon, E., et al.Effect of apocynin, a NADPH oxidase inhibitor, on acute lung inflammationBiochem. Pharmacol.81(5),636-648(2011)
Hashimoto, J., Motohashi, K., Sakamoto, K., et al.Screening and evaluation of new inhibitors of hepatic glucose productionJ. Antibiot. (Tokyo)62(11),625-629(2009)
Hamilton, C.A., Brosnan, M.J., Al-Benna, S., et al.NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vesselsHypertension40(5),755-762(2002)