Sclareol
Cat. No.：YN270448
CAS No. ：515-03-7
| 产品名称: | Sclareol |
| CAS No.: | 515-03-7 |
| Chemical Name: | (αR,1R,2R,4aS,8aS)-α-ethenyldecahydro-2-hydroxy-α,2,5,5,8a-pentamethyl-1-naphthalenepropanol |
| Synonyms: | |
| 分子量: | 308.50 |
| 分子式: | C₂₀H₃₆O₂ |
| SMILES: | CC1(C)CCC[C@@]2(C)[C@@]1([H])CC[C@](O)(C)[C@@H]2CC[C@@](C)(O)C=C |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Sclareol 从Salvia sclarea中分离出来，具有抗癌活性。 Sclareol 对小鼠白血病 (P-388)，人表皮癌 (KB)，以及人白血细胞具有很强的细胞毒活性。Sclareol 诱导细胞凋亡(apoptosis)。 |
| IC50和靶点: | |
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Souza, A.B., de Souza, M.G., Moreira, M.A., et al.Antimicrobial evaluation of diterpenes from Copaifera langsdorffii oleoresin against periodontal anaerobic bacteriaMolecules16(11),9611-9619(2011)
Huang, G.-J., Pan, C.-H., and Wu, C.-H.Sclareol exhibits anti-inflammatory activity in both lipopolysaccharide-stimulated macrophages and the λ-carrageenan-induced paw edema modelJ. Nat. Prod.75(1),54-59(2012)
Dimas, K., Hatziantgoniou, S., Tseleni, S., et al.Sclareol induces apoptosis in human HCT116 colon cancer cells in vitro and suppression of HCT116 tumor growth in immunodeficient miceApoptosis12(4),685-694(2007)
