Atractylenolide III
Cat. No.：YN270450
CAS No. ：73030-71-4
| 产品名称: | Atractylenolide III |
| CAS No.: | 73030-71-4 |
| Chemical Name: | (4aS,8aR,9aS)-4a,5,6,7,8,8a,9,9a-octahydro-9a-hydroxy-3,8a-dimethyl-5-methylene-naphtho[2,3-b]furan-2(4H)-one |
| Synonyms: | ICodonolactone; 8β-Hydroxyasterolide |
| 分子量: | 248.32 |
| 分子式: | C₁₅H₂₀O₃ |
| SMILES: | O=C1C(C)=C(C[C@@]23[H])[C@@](C[C@@]3(C)CCCC2=C)(O)O1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 白术内酯III(Atractylenolide-III)是白术根茎主要成分，有诱导肺癌细胞凋亡活性。 |
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Ji, G.-Q., Chen, R.-Q., and Wang, L.Anti-inflammatory activity of atractylenolide III through inhibition of nuclear factor-κB and mitogen-activated protein kinase pathways in mouse macrophagesImmunopharmacol. Immunotoxicol.38(2),98-102(2016)
Wang, S., Cai, R., Ma, J., et al.The natural compound codonolactone impairs tumor induced angiogenesis by downregulating BMP signaling in endothelial cellsPhytomedicine22(11),1017-1026(2015)
Kang, T.-H., Bang, J.-Y., Kim, M.-H., et al.Atractylenolide III, a sesquiterpenoid, induces apoptosis in human lung carcinoma A549 cells via mitochondria-mediated death pathwayFood Chem. Toxicol.49(2),514-519(2011)
Liu, C., Zhao, H., Ji, Z.-H., et al.Neuroprotection of atractylenolide III from Atractylodis macrocephalae against glutamate-induced neuronal apoptosis via inhibiting caspase signaling pathwayNeurochem. Res.39(9),1753-1758(2014)
Zhao, H., Ji, Z.-H., Liu, C., et al.Neuroprotection and mechanisms of atractylenolide III in preventing learning and memory impairment induced by chronic high-dose homocysteine administration in ratsNeuroscience290,485-491(2015)
