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Cinobufagin

Cat. No.:YN270462

  • CAS No. :470-37-1

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Cinobufagin
      CAS No.: 470-37-1
      Chemical Name: (5β)-16β-(acetyloxy)-14,15β-epoxy-3β-hydroxy-bufa-20,22-dienolide
      Synonyms:Cinobufagine
      分子量:442.54
      分子式:C₂₆H₃₄O₆
      SMILES:C[C@]([C@@H](C(C=C1)=COC1=O)[C@H]2OC(C)=O)(CC[C@@]3([H])[C@@]4([H])CC[C@@]5([H])[C@@]3(CC[C@H](O)C5)C)[C@@]64[C@@H]2O6
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 华蟾酥毒基 (Cinobufagin)是一种天然化合物,具有抗肿瘤的功效。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Tõma, S., Morishita, S., Kuronuma, K., et al.Metabolism and pharmacokinetics of cinobufaginXenobiotica17(10),1195-1202(1987)

      Lu, X.-s., Qiao, Y.-b., Li, Y., et al.Preclinical study of cinobufagin as a promising anti-colorectal cancer agentOncotarget8(1),988-998(2017)

      Xie, S., Spelmink, L., Codemo, M., et al.Cinobufagin modulates human innate immune responses and triggers antibacterial activityPLoS One11(8),e0160734(2016)

      Xu, L., Zhang, X., Feng, Q., et al.Alpha-7 nicotinic receptor-targeted cinobufagin induces antinociception and inhibits NF-κB signaling pathway in DRG neuronsACS Chem. Neurosci.10(1),497-506(2019)

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