Cinobufagin
Cat. No.:YN270462
CAS No. :470-37-1
产品名称: | Cinobufagin |
CAS No.: | 470-37-1 |
Chemical Name: | (5β)-16β-(acetyloxy)-14,15β-epoxy-3β-hydroxy-bufa-20,22-dienolide |
Synonyms: | Cinobufagine |
分子量: | 442.54 |
分子式: | C₂₆H₃₄O₆ |
SMILES: | C[C@]([C@@H](C(C=C1)=COC1=O)[C@H]2OC(C)=O)(CC[C@@]3([H])[C@@]4([H])CC[C@@]5([H])[C@@]3(CC[C@H](O)C5)C)[C@@]64[C@@H]2O6 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | 华蟾酥毒基 (Cinobufagin)是一种天然化合物,具有抗肿瘤的功效。 |
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Tõma, S., Morishita, S., Kuronuma, K., et al.Metabolism and pharmacokinetics of cinobufaginXenobiotica17(10),1195-1202(1987)
Lu, X.-s., Qiao, Y.-b., Li, Y., et al.Preclinical study of cinobufagin as a promising anti-colorectal cancer agentOncotarget8(1),988-998(2017)
Xie, S., Spelmink, L., Codemo, M., et al.Cinobufagin modulates human innate immune responses and triggers antibacterial activityPLoS One11(8),e0160734(2016)
Xu, L., Zhang, X., Feng, Q., et al.Alpha-7 nicotinic receptor-targeted cinobufagin induces antinociception and inhibits NF-κB signaling pathway in DRG neuronsACS Chem. Neurosci.10(1),497-506(2019)