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Loganin

Cat. No.:YN270467

  • CAS No. :18524-94-2

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    • 生物活性
    • 参考文献
    • 产品名称: Loganin
      CAS No.: 18524-94-2
      Chemical Name: 1-(β-D-glucopyranosyloxy)-1S,4aS,5,6S,7R,7aS-hexahydro-6-hydroxy-7-methyl-cyclopenta[c]pyran-4-carboxylic acid, methyl ester
      Synonyms:Loganoside
      分子量:390.38
      分子式:C₁₇H₂₆O₁₀
      SMILES:O[C@H]([C@@H](O)[C@@H]1O)[C@](O[C@@H]1CO)([H])O[C@H]2[C@@]([C@H]3C)([H])[C@@](C[C@@H]3O)([H])C(C(OC)=O)=CO2
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: 马钱苷 (Loganin) 是山茱萸中的主要环烯醚萜苷类化合物,具有抗炎、抗休克的作用。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Kwon, S.-H., Kim, J.-A., Hong, S.-I., et al.Loganin protects against hydrogen peroxide-induced apoptosis by inhibiting phosphorylation of JNK, p38, and ERK 1/2 MAPKs in SH-SY5Y cellsNeurochem Int.58(4),533-541(2011)

      Park, K.S., Kim, B.H., and Chang, I.-M.Inhibitory potencies of several iridoids on cyclooxygenase-1, cyclooxygnase-2 enzymes activities, tumor necrosis factor-α and nitric oxide production in vitroEvid. Based Complement. Alternat. Med.7(1),41-45(2010)

      Yamabe, N., Noh, J.S., Park, C.H., et al.Evaluation of loganin, iridoid glycoside from corni fructus, on hepatic and renal glucolipotoxicity and inflammation in type 2 diabetic db/db MiceEur. J. Pharmacol.648(1-3),179-187(2010)

      Lee, K.Y., Sung, S.H., Kim, S.H., et al.Cognitive-enhancing activity of loganin isolated from Cornus officinalis in scopolamine-induced amnesic miceArch. Pharm. Res.32(5),677-683(2009)

      Liu, K., Xu, H., Lv, G., et al.Loganin attenuates diabetic nephropathy in C57BL/6J mice with diabetes induced by streptozotocin and fed with diets containing high level of advanced glycation end productsLife Sci.123,78-85(2015)

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