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Eriocitrin

Cat. No.:YN270472

  • CAS No. :13463-28-0

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Eriocitrin
      CAS No.: 13463-28-0
      Chemical Name: (2S)-7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2-(3,4-dihydroxyphenyl)-2,3-dihydro-5-hydroxy-4H-1-benzopyran-4-one
      Synonyms:圣草次甙
      分子量:596.53
      分子式:C₂₇H₃₂O₁₅
      SMILES:O=C(C[C@@H](C1=CC(O)=C(O)C=C1)OC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO[C@H](O[C@@H](C)[C@H](O)[C@H]4O)[C@@H]4O)=C5)C2=C5O
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
      Select Batch:
      Purity: 98%
    • 产品描述: Eriocitrin 是一种从柠檬中分离出来的黄酮类化合物,它是一种强效的抗氧化剂。Eriocitrin 通过上调 p53,cyclin A,cyclin D3 和CDK6 使 S 期细胞周期停滞,从而抑制肝癌细胞的增殖。Eriocitrin 通过激活线粒体涉及的内在信号传导途径来触发细胞凋亡。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Horowitz, R.M., and Gentili, B.Flavonoid compounds of citrus. III. Isolation and structure of eriodictyol glycosideJ. Am. Chem. Soc.82(11),2803-2806(1960)

      Miyake, Y., Yamamoto, K., and Osawa, T.Isolation of eriocitrin (eriodictyol 7-rutinoside) from lemon fruit (Citrus limon BURM. f.) and its antioxidative activityFood Sci. Technol. Int. Tokyo3(1),84-89(1997)

      Miyake, Y., Shimoi, K., Kumazawa, S., et al.Identification and antioxidant activity of flavonoid metabolites in plasma and urine of eriocitrin-treated ratsJ. Agric. Food Chem.48(8),3217-3224(2000)

      Minato, K., Miyake, Y., Fukumoto, S., et al.Lemon flavonoid, eriocitrin, suppresses exercise-induced oxidative damage in rat liverLife Sci.72(14),1609-1616(2003)

      Carradori, S., Gidaro, M.C., Petzer, A., et al.Inhibition of human monoamine oxidase: Biological and molecular modeling studies on selected natural flavonoidsJ. Agric. Food Chem.64(47),9004-9011(2016)

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