Rhapontin
Cat. No.：YN270473
| 产品名称: | Rhapontin |
| CAS No.: | 155-58-8 |
| Chemical Name: | 3-hydroxy-5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]phenyl-β-D-glucopyranoside |
| Synonyms: | 土大黄苷; Rhaponiticin |
| 分子量: | 420.41 |
| 分子式: | C₂₁H₂₄O₉ |
| SMILES: | O[C@H]([C@@H](O)[C@@H]1O)[C@@H](O[C@@H]1CO)OC2=CC(/C=C/C3=CC(O)=C(OC)C=C3)=CC(O)=C2 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Rhapontin (Rhaponiticin) 是Rheum officinale Baillon的一种成分。Rhaponiticin 可诱导凋亡 (apoptosis)，从而抑制人胃癌 KATO III 细胞增殖。 |
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Chun, Y.J., Ryu, S.Y., Jeong, T.C., et al.Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigeninDrug Metab. Dispos.29(4),389-393(2001)
Roupe, K.A., Helms, G.L., Halls, S.C., et al.Preparative enzymatic synthesis and HPLC analysis of rhapontigenin: Applications to metabolism, pharmacokinetics and anti-cancer studiesJ. Pharm. Pharm. Sci.8(3),374-386(2005)
Roberti, M., Pizzirani, D., Simoni, D., et al.Synthesis and biological evaluation of resveratrol and analogues as apoptosis-inducing agentsJ. Med. Chem.46(16),3546-3554(2003)
Kim, J.-K., Kim, N., and Lim, Y.-H.Evaluation of the antibacterial activity of rhapontigenin produced from rhapontin by biotransformation against Propionibacterium acnesJ. Microbiol. Biotechnol.20(1),82-87(2010)
Lee, H.-S., Kim, J.-K., Park, K.-T., et al.Rhapontigenin converted from rhapontin purified from Rheum undulatum enhances the inhibition of melanin synthesisBiosci. Biotechnol. Biochem.76(12),2307-2309(2012)
