Icaritin
Cat. No.：YN270474
| 产品名称: | Icaritin |
| CAS No.: | 118525-40-9 |
| Chemical Name: | 3,5,7-trihydroxy-2-(4-methoxyphenyl)-8-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one |
| Synonyms: | Anhydroicaritin |
| 分子量: | 368.38 |
| 分子式: | C₂₁H₂₀O₆ |
| SMILES: | O=C1C(O)=C(C2=CC=C(OC)C=C2)OC3=C(C/C=C(C)\C)C(O)=CC(O)=C13 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Icaritin (Anhydroicaritin) 是Epimedium Genusis的异戊二烯类黄酮衍生物，有效抑制 K562 细胞 (IC50为 8 µM) 和原代 CML 细胞 (对 CML-CP 的IC50值为 13.4 µM，对 CML-BC 的IC50值为 18 µM) 的增殖。Icaritin 可以调节MAPK/ERK/JNK和JAK2/STAT3/AKT信号传导，并具有增强成骨的作用。 |
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| Solvent & Solubility: |
Wu, J., Du, J., Fu, X., et al.Iciartin, a novel FASN inhibitor, exerts anti-melanoma activities through IGF-1R/STAT3 signalingOncotarget,(2016)
