Tubeimoside I
Cat. No.：YN270490
CAS No. ：102040-03-9
| 产品名称: | Tubeimoside I |
| CAS No.: | 102040-03-9 |
| Chemical Name: | (2β,3β,4α)-olean-12-en-28-oic acid, 3-[[2-O-[4-O-[(3S)-4-carboxy-3-hydroxy-3-methyl-1-oxobutyl]-α-L-arabinopyranosyl]-β-D-glucopyranosyl]oxy]-2,23-dihydroxy-28-(O-β-D-xylopyranosyl-(1→3)-O-6-deoxy-α-L-mannopyranosyl-(1→2)-α-L-arabinopyranosyl) ester, intr |
| Synonyms: | Tubeimoside-1; Lobatoside-H |
| 分子量: | 1319.44 |
| 分子式: | C₆₃H₉₈O₂₉ |
| SMILES: | O=C(O[C@H](OCC(O)[C@H]1O)[C@@H]1OC(OC(C)C(OC(CC(O)(CC(O[C@@H]2[C@H]3O)=O)C)=O)C4OC(OCC(O)C5O)C5O)C4O)C6(CCC(C)(C)C7)C7C8=CCC9C(C)(CCC%10C9(CC(O)C(OC(OC(CO)C(O)C%11O)C%11O[C@H](OC2)[C@@H]3O)C%10(C)CO)C)C8(C)CC6 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | 土贝母苷甲(Tubeimoside I)是中药土贝母提取物，已被证明为人类各种癌症的一种有效的抗肿瘤剂。 |
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Wang, Y., Deng, L., Zhong, H., et al.Natural plant extract tubeimoside I promotes apoptosis-mediated cell death in cultured human hepatoma (HepG2) cellsBiol. Pharm. Bull.34(6),831-838(2011)
Xu, Y., Chiu, J.F., He, Q.Y., et al.Tubeimoside-1 exerts cytotoxicity in HeLa cells through mitochondrial dysfunction and endoplasmic reticulum stress pathwaysJ. Proteome Res.8(3),1585-1593(2009)
Gu, Y., Körbel, C., Scheuer, C., et al.Tubeimoside-1 suppresses tumor angiogenesis by stimulation of proteasomal VEGFR2 and Tie2 degradation in a non-small cell lung cancer xenograft modelOncotarget7(5),5258-5272(2016)
Peng, Y., Zhong, Y., and Li, G.Tubeimoside-1 suppresses breast cancer metastasis through downregulation of CXCR4 chemokine receptor expressionBMB Rep.49(9),502-507(2016)
