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Sophoraflavanone G

Cat. No.:YN270492

  • CAS No. :97938-30-2

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Sophoraflavanone G
      CAS No.: 97938-30-2
      Chemical Name: (2S)-2-(2,4-dihydroxyphenyl)-2,3-dihydro-5,7-dihydroxy-8-[(2R)-5-methyl-2-(1-methylethenyl)-4-hexen-1-yl]-4H-1-benzopyran-4-one
      Synonyms:Kushenol F
      分子量:424.49
      分子式:C₂₅H₂₈O₆
      SMILES:O=C1C[C@@H](C2=CC=C(O)C=C2O)OC3=C(C[C@H](C(C)=C)C/C=C(C)\C)C(O)=CC(O)=C13
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Sophoraflavanone G (Kushenol F) 是从苦参中提取得到的,具有抗肿瘤和抗炎特性。Sophoraflavanone G (Kushenol F) 通过抑制 MAPK 相关途径诱导 MDA-MB-231 和 HL-60 细胞凋亡 (apoptosis)。
      IC50和靶点:
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    • Sato, M., Tsuchiya, H., Takase, I., et al.Antibacterial activity of flavanone isolated from Sophora exigua against methicillin-resistant Staphylococcus aureus and its combination with antibioticsPhytother. Res.9(7),509-512(1995)

      Kim, J.H., Ryu, Y.B., Kang, N.S., et al.Glycosidase inhibitory flavonoids from Sophora flavescensBiol. Pharm. Bull.29(2),302-305(2006)

      Ko, W.G., Kang, T.H., Kim, N.Y., et al.Lavandulylfavonoids: A new class of in vitro apoptogenic agents from Sophora favescensToxicol. In Vitro14(5),429-433(2000)

      Kim, D.W., Chi, Y.S., Son, K.H., et al.Effects of sophoraflavanone G, a prenylated flavonoid from Sophora flavescens, on cyclooxygenase-2 and in vivo inflammatory responseArch. Pharm. Res.25(3),329-335(2002)

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