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Sophoridine

Cat. No.:YN270493

  • CAS No. :6882-68-4

    • 产品资料
    • 生物活性
    • 参考文献
    • 产品名称: Sophoridine
      CAS No.: 6882-68-4
      Chemical Name: (7aR,13aR,13bR,13cS)-dodecahydro-1H,5H,10H-dipyrido[2,1-f:3′,2′,1′-ij][1,6]naphthyridin-10-one
      Synonyms:槐定碱
      分子量:248.36
      分子式:C₁₅H₂₄N₂O
      SMILES:O=C1CCC[C@]2([H])[C@@]3([H])CCCN4[C@@]3([H])[C@@](CCC4)([H])CN21
      存储:Please store the product under the recommended conditions in theCertificate of Analysis.
      运输:Room temperature in continental US; may vary elsewhere.
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      Purity: 98%
    • 产品描述: Sophoridine 是一种从豆科植物槐豆斜生植物的叶子中分离出来的喹喔啉生物碱。Sophoridine 诱导细胞凋亡 (apoptosis)。Sophoridine 有可能成为胰腺癌的有效,选择性和耐受性良好的候选药物。
      IC50和靶点:
      In Vitro:
      In Vivo:
      Clinical Trial:
      Solvent & Solubility:
    • Liang, L., Wang, X.-Y., Zhang, X.-H., et al.Sophoridine exerts an anti-colorectal carcinoma effect through apoptosis induction in vitro and in vivoLife Sci.91(25-26),1295-1303(2012)

      Zhang, Y., Zhu, H., Ye, G., et al.Antiviral effects of sophoridine against coxsackievirus B3 and its pharmacokinetics in ratsLife Sci.78(17),1998-2005(2006)

      Huang, X., Li, B., and Shen, L.Studies on the anti-inflammatory effect and its mechanisms of sophoridineJ. Anal. Methods Chem.,502626(2014)

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