Periplocin
Cat. No.：YN270494
CAS No. ：13137-64-9
| 产品名称: | Periplocin |
| CAS No.: | 13137-64-9 |
| Chemical Name: | (3β,5β)-3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-card-20(22)-enolide |
| Synonyms: | Periplocoside,杠柳毒苷 |
| 分子量: | 696.82 |
| 分子式: | C₃₆H₅₆O₁₃ |
| SMILES: | O=C1OCC([C@H]2CC[C@]3(O)[C@]([C@]4([H])CC[C@@]32C)([H])CC[C@]([C@]4(C)CC5)(O)C[C@H]5O[C@@](O[C@@H]6C)([H])C[C@H](OC)[C@@H]6O[C@]7([H])O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)=C1 |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Periplocin 是一类从Periploca forrestii中分离出的强心类固醇。Periplocin 可促进肿瘤细胞凋亡并抑制肿瘤生长。Periplocin 通过激活 Na/K-ATPase 介导的 Src/ERK 和 PI3K/Akt 途径而具有促进伤口愈合的潜力。 |
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Cheng, C.-F., Lu, I.-H., Tseng, H.-W., et al.Antitumor effect of periplocin in TRAIL-resistant human hepatocellular carcinoma cells through downregulation of IAPsEvid. Based Complement. Altnernat. Med.2013,958025(2013)
Wang, X.-y., Gao, X.-m., Liu, H., et al.Gene expression profiling of the proliferative effect of periplocin on mouse cardiac microvascular endothelial cellsChin. J. Integr. Med.16(1),33-40(2010)
Li, Y., Li, J., Zhou, K., et al.A review on phytochemistry and pharmacology of Cortex PeriplocaeMolecules21(12),E1702(2016)
Lu, Z.J., Zhou, Y., Song, Q., et al.Periplocin inhibits growth of lung cancer in vitro and in vivo by blocking AKT/ERK signaling pathwaysCell Physiol. Biochem.26(4-5),609-618(2010)
Li, L., Zhao, L.-M., Dai, S.-l., et al.Periplocin extracted from cortex periplocae induced apoptosis of gastric cancer cells via the ERK1/2-EGR1 pathwayCell Physiol. Biochem.38(5),1939-1951(2016)
