Didymin
Cat. No.:YN270509
产品名称: | Didymin |
CAS No.: | 14259-47-3 |
Chemical Name: | (2S)-7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
Synonyms: | Neoponcirin,Isosakuranetin-7-O-rutinoside,香风草甙 |
分子量: | 594.56 |
分子式: | C₂₈H₃₄O₁₄ |
SMILES: | O=C1C[C@@H](C2=CC=C(OC)C=C2)OC3=CC(O[C@H]4[C@@H]([C@H]([C@@H]([C@@H](CO[C@H]5[C@@H]([C@@H]([C@H]([C@H](C)O5)O)O)O)O4)O)O)O)=CC(O)=C13 |
存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
运输: | Room temperature in continental US; may vary elsewhere. |
产品描述: | Didymin从柑橘类水果中提取的一种膳食类黄酮苷,具有抗氧化特性。Didymin 通过抑制 N-Myc 和上调 RKIP 诱导凋亡。 |
IC50和靶点: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: |
Morelli, S., Piscioneri, A., Salerno, S., et al.Neuroprotective effect of didymin on hydrogen peroxide-induced injury in the neuronal membrane systemCells Tissues Organs199(2-3),184-200(2014)
Hung, J.-Y., Hsu, Y.-L., Ko, Y.-C., et al.Didymin, a dietary flavonoid glycoside from citrus fruits, induces Fas-mediated apoptotic pathway in human non-small-cell lung cancer cells in vitro and in vivoLung Cancer68(3),366-374(2010)
Lin, X., Bai, F., Nie, J., et al.Didymin alleviates hepatic fibrosis through inhibiting ERK and PI3K/Akt pathways via regulation of Raf kinase inhibitor proteinCell Physiol. Biochem.40(6),1422-1432(2016)