Poncirin
Cat. No.：YN270515
CAS No. ：14941-08-3
| 产品名称: | Poncirin |
| CAS No.: | 14941-08-3 |
| Chemical Name: | (2S)-7-[[2-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
| Synonyms: | Isosakuranetin-7-neohesperidoside,枸橘苷 |
| 分子量: | 594.56 |
| 分子式: | C₂₈H₃₄O₁₄ |
| SMILES: | O=C(C[C@@H](C1=CC=C(OC)C=C1)OC2=CC(O[C@H](O[C@H](CO)[C@@H](O)[C@@H]3O)[C@@H]3O[C@@](O[C@@H](C)[C@H](O)[C@H]4O)([H])[C@@H]4O)=C5)C2=C5O |
| 存储: | Please store the product under the recommended conditions in theCertificate of Analysis. |
| 运输: | Room temperature in continental US; may vary elsewhere. |
| 产品描述: | Poncirin 是从三叶草中分离出来的，具有抗炎活性。 在完全弗氏佐剂 (CFA) 诱发的炎症性疼痛小鼠模型中，Poncirin 显着降低了机械性痛觉过敏和异常性疼痛。 |
| IC50和靶点: | |
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Mouly, P., Gaydou, E.M., and Auffray, A.Simultaneous separation of flavanone glycosides and polymethoxylated flavones in citrus juices using liquid chromatographyJ. Chromatogr. A800(2),171-179(1998)
Zhu, X., Luo, F., Zheng, Y., et al.Characterization, purification of Poncirin from edible Citrus Ougan (Citrus reticulate cv. Suavissima) and its growth inhibitory effect on human gastric cancer cells SGC-7901Int. J. Mol. Sci.14(5),8684-8697(2013)
Kim, J.-B., Han, A.-R., Park, E.-Y., et al.Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-κB inactivation in RAW 264.7 macrophage cellsBiol. Pharm. Bull.30(12),2345-2351(2007)
Lee, J.-H., Lee, S.-H., Kim, Y.S., et al.Protective effects of neohesperidin and poncirin isolated from the fruits of Poncirus trifoliata on potential gastric diseasePhytother. Res.23(12),1748-1753(2009)
